Dual-site interactions of p53 protein transactivation domain with anti-apoptotic Bcl-2 family proteins reveal a highly convergent mechanism of divergent p53 pathways*

Keywords : p53 transactivation domain (p53TAD), Bcl-2 family proteins

2020-01-15    |    1130

Structural mechanism of the arrestin-3/JNK3 interaction

Keywords : MAPK scaffolding, Arrestin-mediated MAPK activation, Arrestin-3 and JNK3

2019-11-08    |    1161

Identification of HLA-DR4-restricted immunogenic peptide derived from xenogenic porcine major histocompatibility complex class I molecule

Keywords : HLA-DR4, Indirect recognition, Swine leukocyte antigen, Xenorecognition

2019-11-06    |    1270

Identification of HLA-A2-restricted immunogenic peptides derived from a xenogenic porcine major histocompatibility complex

Keywords : HLA-A2, Indirect recognition, Swine leukocyte Antigen, Xenorecognition

2019-11-06    |    1013

Innate-like cytotoxic function of bystander-activated CD8+ T Cells is associated with liver injury in acute hepatitis A

Keywords : Acute Hepatitis A, Bystander-Activated CD8+ T Cell, CMV peptide

2019-10-29    |    1497

RNAi-mediated silencing of TNF-α converting enzyme to down-regulate soluble TNF-α production for treatment of acute and chronic colitis

Keywords : RNA interference, Tumor necrosis factor-α, TNF-α converting enzyme

2019-09-10    |    1195

The targeted delivery of the c-Src peptide complexed with schizophyllan to macrophages inhibits polymicrobial sepsis and ulcerative colitis in mice

Keywords : Schizophyllan, c-Src, Reactive oxygen species, Sepsis, Colitis

2019-09-10    |    1290

Peptide inhibition of p22phox and rubicon interaction as a therapeutic strategy for septic shock

Keywords : Sepsis, p22phox, Rubicon, Reactive oxygen species

2019-09-10    |    1364

Human prion protein-induced autophagy flux governs neuron cell damage in primary neuron cells

Keywords : Prion protein, Autophagy flux, Neurodegeneration, PrPc, ATG5, Gerotarget

2019-05-29    |    1519

Neuroprotective effect of cellular prion protein (PrPC) is related with activation of alpha7 nicotinic acetylcholine receptor(α7nAchR)-mediated autophagy flux

Keywords : Autophagy flux, Alpha-7 nicotinic receptor, Prpc, Prion, Geotarget

2019-05-29    |    1741