Dual-site interactions of p53 transactivation domain with anti-apoptotic Bcl-2 family proteins reveal a highly convergent mechanism of divergent p53 pathways

Keywords : p53, Bcl-2 family protein, dual-site interaction, apoptosis, NMR, structure

2014-07-17    |    4130

Structural basis for the conserved binding mechanism of MDM2-inhibiting peptides and anti-apoptotic Bcl-2 family proteins

Keywords : p53 transactivation domain, MDM2-inhibiting peptide, Bcl-2 family proteins, NMR spectroscopy, Dua...

2014-07-17    |    2408

Therapeutic effects of a reducible poly (oligo-D-arginine) carrier with the heme oxygenase-1 gene in the treatment of hypoxic-ischemic brain injury

Keywords : Gene therapy, Gene expression, Peptide, In vivo test, Animal model

2014-07-17    |    2613

Synthetic Peptides Containing ITIM-Like Domains Block Expression of Inflammatory Mediators and Migration & Invasion of Cancer Cells Through Activation of SHP-1 and PI3K

Keywords : ITIM, IREM-1, Invasion, Migration, Inflammation, Cancer 

2014-07-10    |    3241

SNX18 shares a redundant role with SNX9 and modulates endocytic trafficking at the plasma membrane

Keywords : SNX18, SNX9, Clathrin-mediated endocytosis, Dynamin, Membrane tubulation

2014-07-10    |    3033

POLYPEPTIDE LINKER AND METHOD OF ANALYZING TARGET MATERIAL USING THE SAME

2014-07-10    |    2535

Method for screening osteopontin inhibitor and inhibitor prepared thereby

2014-07-10    |    2859

LYM2-dependent chitin perception limits molecular flux via plasmodesmata

2014-07-10    |    2875

Invariant NKT Cells Producing IL-4 or IL-10, But Not IFN- g, Inhibit the Th1 Response in Experimental Autoimmune Encephalomyelitis, Whereas None of These Cells Inhibits the Th17 Response

2014-07-10    |    2948

Inhibitory Activity of Alternative Splice Variants of the Bullfrog GnRH Receptor-3 on Wild-Type Receptor Signaling

2014-07-10    |    2595